(CNN)A massive explosion rocked the Lebanese capital of Beirut on Tuesday evening, leaving dozens dead and thousands injured.

The blast has been linked to a large supply of confiscated and potentially unsecured explosive material, stored in a warehouse at the city’s port, close to populated areas. As world leaders and international organizations step in to offer assistance, local officials are also launching an investigation into the blast. Authorities were scrambling Wednesday to treat the wounded, search for survivors, and assess the full extent of the damage. Here’s what we know so far.The basics: What, where, whenRead MoreThe explosion took place at 6:07 p.m. local time near Beirut’s port and central district, close to many highly-populated areas and tourist sites. Nearby landmarks include the historic Martyrs’ Square; the Gemmayzeh and Mar Mikhael neighborhoods, fixtures of the Beirut bar scene; the landmark Mohammad Al-Amin Mosque; Grand Serail, the government palace; and Baabda Palace, the official residence of the Lebanese President.The explosion tore through the city, flipping cars, shattering glass and causing some homes to crumble. Damaged buildings include the headquarters of former Prime Minister Saad Hariri and CNN’s bureau in downtown Beirut. Homes as far as 10 kilometers (6 miles) away were damaged, according to witnesses. Beirut’s governor Marwan Abboud told reporters that the explosion has resulted in an estimated three to five billion US dollars’ worth of damage. NNA, Lebanon’s state-run media, reported that 90% of hotels in the Lebanese capital had been damaged. The blast was even felt in Cyprus, around 240 kilometers (150 miles) away, and registered as a 3.3 magnitude earthquake. What are the casualties?At least 100 people were killed in the blast and more than 4,000 wounded, according to the state-run National News Agency (NNA), which cited the Red Cross. The death toll is expected to continue rising throughout the day, said Health Minister Hamad Hassan in a phone interview Wednesday morning with one of Lebanon’s national television channels. “There are many people missing until now. People are asking the emergency department about their loved ones and it is difficult to search at night because there is no electricity. We are facing a real catastrophe and need time to assess the extent of damages,” Hasan said in a Reuters report.Among the dead are the secretary-general of the Kataeb political party, Nazar Najarian, according to NNA. He was in his office when the explosion happened, and died after being critically injured.At least 10 firefighters working for Beirut’s municipality are missing, said the city’s governor Marwan Abboud. At least one Australian was killed, and the Australian Embassy building has been “significantly compromised,” said Australian Prime Minister Scott Morrison. Two Filipino citizens also died from the explosion, and eight others are injured, said a statement from the Philippine Embassy in Beirut. Eleven other Filipino seafarers are still missing.One Japanese citizen, one Indonesian, and six Turkish citizens were also injured, according to authorities from the three countries.Some naval peacekeepers with the United Nations Interim Force in Lebanon (UNIFIL) have also been injured, some seriously. They have been transported to hospital for treatment, said UNIFIL. What caused the blast?In the immediate aftermath, there were conflicting reports, and it was initially blamed on a major fire at a warehouse for firecrackers near the port. United States President Donald Trump added to the confusion when he referred to the incident at an “attack,” though US Defense Department officials told CNN afterward there was no indication that was the case. Lebanese officials also raised concerns with US diplomats about the use of the phrase “attack,” two State Department officials said. Later, in the early hours of Wednesday morning, Prime Minister Hassan Diab said that about 2,750 metric tons of ammonium nitrate, a highly explosive material, had been stored at a port warehouse for the past six years “without preventive measures.” Lebanon’s general security chief said a “highly explosive material” had been confiscated years earlier and stored in the warehouse, which is just a few minutes’ walk from Beirut’s shopping and nightlife districts. The aftermath of an explosion is seen in Beirut, Lebanon, on Wednesday, August 5.The aftermath of an explosion is seen in Beirut, Lebanon, on Wednesday, August 5. Photos: Huge explosion rocks BeirutThe aftermath of an explosion is seen in Beirut, Lebanon, on Wednesday, August 5.Hide Caption 1 of 29Debris hangs Wednesday from a damaged facade in Beirut.Debris hangs Wednesday from a damaged facade in Beirut. Photos: Huge explosion rocks BeirutDebris hangs Wednesday from a damaged facade in Beirut.Hide Caption 2 of 29Lebanese soldiers search for survivors on Wednesday.Lebanese soldiers search for survivors on Wednesday. Photos: Huge explosion rocks BeirutLebanese soldiers search for survivors on Wednesday.Hide Caption 3 of 29The Beirut neighborhood of Mar Mikhael sits Wednesday in ruins.The Beirut neighborhood of Mar Mikhael sits Wednesday in ruins. Photos: Huge explosion rocks BeirutThe Beirut neighborhood of Mar Mikhael sits Wednesday in ruins.Hide Caption 4 of 29A damaged hospital room is seen on Wednesday.A damaged hospital room is seen on Wednesday. Photos: Huge explosion rocks BeirutA damaged hospital room is seen on Wednesday.Hide Caption 5 of 29A man takes pictures of destroyed buildings on Wednesday.A man takes pictures of destroyed buildings on Wednesday. Photos: Huge explosion rocks BeirutA man takes pictures of destroyed buildings on Wednesday.Hide Caption 6 of 29People walk Wednesday along a road littered with debris and abandoned vehicles.People walk Wednesday along a road littered with debris and abandoned vehicles. Photos: Huge explosion rocks BeirutPeople walk Wednesday along a road littered with debris and abandoned vehicles.Hide Caption 7 of 29A helicopter fights a fire on Tuesday, August 4, at the scene of an explosion in Beirut, Lebanon.A helicopter fights a fire on Tuesday, August 4, at the scene of an explosion in Beirut, Lebanon. Photos: Huge explosion rocks BeirutA helicopter fights a fire on Tuesday, August 4, at the scene of an explosion in Beirut, Lebanon.Hide Caption 8 of 29Rescue crews search a street for survivors  on Tuesday night. "People are asking the emergency department about their loved ones, and it is difficult to search at night because there is no electricity," Health Minister Hamad Hassan <a href="https://www.cnn.com/middleeast/live-news/lebanon-beirut-explosion-live-updates-dle-intl/h_191ad60f239ae9b49e4332022ce8db8c" target="_blank">told the Reuters news agency.</a> "We are facing a real catastrophe and need time to assess the extent of damages."Rescue crews search a street for survivors  on Tuesday night. "People are asking the emergency department about their loved ones, and it is difficult to search at night because there is no electricity," Health Minister Hamad Hassan <a href="https://www.cnn.com/middleeast/live-news/lebanon-beirut-explosion-live-updates-dle-intl/h_191ad60f239ae9b49e4332022ce8db8c" target="_blank">told the Reuters news agency.</a> "We are facing a real catastrophe and need time to assess the extent of damages." Photos: Huge explosion rocks BeirutRescue crews search a street for survivors on Tuesday night. “People are asking the emergency department about their loved ones, and it is difficult to search at night because there is no electricity,” Health Minister Hamad Hassan told the Reuters news agency. “We are facing a real catastrophe and need time to assess the extent of damages.”Hide Caption 9 of 29A wounded man is helped as he walks through debris following the explosion.A wounded man is helped as he walks through debris following the explosion. Photos: Huge explosion rocks BeirutA wounded man is helped as he walks through debris following the explosion.Hide Caption 10 of 29Smoke rises after the blast. This image was obtained from a video on social media.Smoke rises after the blast. This image was obtained from a video on social media. Photos: Huge explosion rocks BeirutSmoke rises after the blast. This image was obtained from a video on social media.Hide Caption 11 of 29Lebanese Red Cross officers carry an injured woman on Tuesday night.Lebanese Red Cross officers carry an injured woman on Tuesday night. Photos: Huge explosion rocks BeirutLebanese Red Cross officers carry an injured woman on Tuesday night.Hide Caption 12 of 29A building's facade is shattered after Tuesday's explosion.A building's facade is shattered after Tuesday's explosion. Photos: Huge explosion rocks BeirutA building’s facade is shattered after Tuesday’s explosion.Hide Caption 13 of 29Wounded people wait to received help outside a hospital. Emergency wards have been inundated.Wounded people wait to received help outside a hospital. Emergency wards have been inundated. Photos: Huge explosion rocks BeirutWounded people wait to received help outside a hospital. Emergency wards have been inundated.Hide Caption 14 of 29An investigation into the explosion was announced by Lebanese Prime Minister Hassan Diab.An investigation into the explosion was announced by Lebanese Prime Minister Hassan Diab. Photos: Huge explosion rocks BeirutAn investigation into the explosion was announced by Lebanese Prime Minister Hassan Diab.Hide Caption 15 of 29People run for cover following the explosion. Bachar Ghattas, an eyewitness, described scenes of chaos: "You can see injured people all over the streets in Beirut, glass all over the place, cars are damaged. It is like an apocalypse."People run for cover following the explosion. Bachar Ghattas, an eyewitness, described scenes of chaos: "You can see injured people all over the streets in Beirut, glass all over the place, cars are damaged. It is like an apocalypse." Photos: Huge explosion rocks BeirutPeople run for cover following the explosion. Bachar Ghattas, an eyewitness, described scenes of chaos: “You can see injured people all over the streets in Beirut, glass all over the place, cars are damaged. It is like an apocalypse.”Hide Caption 16 of 29Injured people sit on a street after the blast.Injured people sit on a street after the blast. Photos: Huge explosion rocks BeirutInjured people sit on a street after the blast.Hide Caption 17 of 29Lebanese soldiers watch as a helicopter fights a fire at the scene of the explosion.Lebanese soldiers watch as a helicopter fights a fire at the scene of the explosion. Photos: Huge explosion rocks BeirutLebanese soldiers watch as a helicopter fights a fire at the scene of the explosion.Hide Caption 18 of 29A man sits near the site of the blast.A man sits near the site of the blast. Photos: Huge explosion rocks BeirutA man sits near the site of the blast.Hide Caption 19 of 29Firefighters work at the scene on Tuesday.Firefighters work at the scene on Tuesday. Photos: Huge explosion rocks BeirutFirefighters work at the scene on Tuesday.Hide Caption 20 of 29A wounded person is carried after the blast.A wounded person is carried after the blast. Photos: Huge explosion rocks BeirutA wounded person is carried after the blast.Hide Caption 21 of 29The explosion was near the port in the Lebanese capital.The explosion was near the port in the Lebanese capital. Photos: Huge explosion rocks BeirutThe explosion was near the port in the Lebanese capital.Hide Caption 22 of 29Smoke billows following the explosion.Smoke billows following the explosion. Photos: Huge explosion rocks BeirutSmoke billows following the explosion.Hide Caption 23 of 29A wounded man walks near the scene.A wounded man walks near the scene. Photos: Huge explosion rocks BeirutA wounded man walks near the scene.Hide Caption 24 of 29People gather by damaged buildings after the blast.People gather by damaged buildings after the blast. Photos: Huge explosion rocks BeirutPeople gather by damaged buildings after the blast.Hide Caption 25 of 29Firefighters use a water hose on flaming debris.Firefighters use a water hose on flaming debris. Photos: Huge explosion rocks BeirutFirefighters use a water hose on flaming debris.Hide Caption 26 of 29Red smoke rises after the explosion, which could be felt for miles. "What I felt was that it was an earthquake," Beirut resident Rania Masri told CNN.Red smoke rises after the explosion, which could be felt for miles. "What I felt was that it was an earthquake," Beirut resident Rania Masri told CNN. Photos: Huge explosion rocks BeirutRed smoke rises after the explosion, which could be felt for miles. “What I felt was that it was an earthquake,” Beirut resident Rania Masri told CNN.Hide Caption 27 of 29People walk near the scene of the explosion.People walk near the scene of the explosion. Photos: Huge explosion rocks BeirutPeople walk near the scene of the explosion.Hide Caption 28 of 29A man reacts at the scene soon after the explosion.A man reacts at the scene soon after the explosion. Photos: Huge explosion rocks BeirutA man reacts at the scene soon after the explosion.Hide Caption 29 of 2901 beirut aftermath 080504 beirut aftermath 080507 beirut aftermath 080505 beirut aftermath 080506 beirut aftermath 080502 beirut aftermath 080503 beirut aftermath 080526 beirut explosion 080429 beirut explosion 080425 beirut explosion 080409 beirut explosion 080430 beirut explosion 080421 beirut explosion 0804 RESTRICTED22 beirut explosion 080418 beirut explosion 080412 beirut explosion 080431 beirut explosion 0804 RESTRICTED16 beirut explosion 080424 beirut explosion 0804 RESTRICTED14 beirut explosion 080419 beirut explosion 080427 beirut explosion 080406 beirut explosion 080403 beirut explosion 0804RESTRICTED 07 beirut explosion 080411 beirut explosion 080415 beirut explosion 080405 beirut explosion 080413 beirut explosion 0804Officials have so far not commented on what might have ignited the blaze. Diab announced an investigation into the explosion, saying the probe would include “revelations that will be announced about this dangerous warehouse which has been present since 2014.””I will not rest until we find those responsible for what happened, hold them accountable, and impose maximum punishment,” he said in a statement, saying it was “unacceptable” that so much ammonium nitrate had been stored “while endangering the safety of citizens.”However, experts have cautioned that the blast could have been caused by more than just ammonium nitrate.Anthony May, a retired ATF explosives investigator for the US government, said the color of the cloud after the blast suggests there may have been other compounds involved. And Robert Baer, a former CIA operative with extensive experience in the Middle East, said “that orange ball (of fire)” indicated possible military grade explosives.What is ammonium nitrate?Ammonium nitrate (AN), a compound of ammonia and nitrogen, is a highly volatile material used in agricultural fertilizers and bombs.Disasters involving AN are rare, considering the US uses millions of tons of it every year in fertilizers, according to the Environmental Protection Agency. “Pure” solid AN is quite stable, but if the compound is mixed with any contaminants, even in small traces, the mixture becomes much more prone to detonation — which is why there are normally stringent government guidelines for how to treat and store it properly.”In general, the conditions of AN storage are crucial to the safety and stability of the AN. Materials co-located or stored with AN may play a role in its sensitivity to explosion,” said the EPA in a 2015 guide.For instance, AN shouldn’t be stored with any fuel, organic materials, chlorides or metals, said the guide — all potential contaminants. The EPA guidelines also recommend fire resistant walls in the storage unit, noncombustible flooring, and — crucially — controlled temperatures.AN doesn’t burn, but if exposed to heat, it can melt — which releases combustible toxic gases that can cause an explosion. It’s even more dangerous if there is a large supply of AN all stored together, because once a small section of AN begins to melt and explode, the resulting heat can set off the rest of the supply.One of the worst disasters in US history involving a form of ammonia occurred in April 1947 when a ship loaded with ammonium nitrate caught fire while docked in Texas City. The fire caused an explosion and additional fires that damaged more than 1,000 buildings and killed nearly 400 people, according to the website of the Texas Historical Association.For perspective, that explosion was triggered by 2,300 US tons (about 2087 metric tons) of ammonium nitrate, according to US Homeland Security. And the 1995 Oklahoma City Bombing, a US domestic terror attack that killed 169 people and injured 467, used only two US tons (1.8 metric tons) of ammonium nitrate.What are the ongoing response efforts?In the hours following the bombing, authorities and humanitarian organizations launched search and rescue efforts. The Lebanese President has directed all armed forces to respond to the disaster, and to patrol affected areas for additional security. Lebanon has allocated 100 billion Lebanese pounds — which, according to the government rate, is about $66,335,000 — to deal with the effects of the blast, the Levbanese Presidency Twitter account said Wednesday.Aid groups like UNICEF and the Red Cross have teams on the ground assisting authorities, and have put out urgent open calls for blood donations.Hospitals were quickly inundated, with doctors conducting triage as dozens flooded into emergency rooms. The emergency section of one major hospital, the American University of Beirut Medical Center, became unable to receive more patients. Four hospitals are out of service after sustaining damage in the explosion, said the health minister.Ammonium nitrate stored in a warehouse linked to catastrophic Beirut explosionAmmonium nitrate stored in a warehouse linked to catastrophic Beirut explosionAmmonium nitrate stored in a warehouse linked to catastrophic Beirut explosionThe Lebanese Red Cross said on Wednesday that multiple temporary shelters with food, hygiene kits and basic needs have been set up to receive 1,000 families for 72 hours.Other countries and international organizations quickly stepped in to help, and the United Nations and World Health Organization are working with Lebanese authorities.President Trump, Australian Prime Minister Morrison and Russian President Vladimir Putin all offered support and assistance. Russia has sent five planes carrying medical equipment and a team of doctors to set up a field hospital in Beirut, according to state news agency TASS, which cited the Russian Ministry of Emergency Situations.French President Emmanuel Macron said “rescue and aid” were on the way to Lebanon, and Israel has formally extended humanitarian medical assistance.The spokesman for Egypt’s Ministry of Foreign Affairs said the Egyptian field hospital in Beirut was ready to provide assistance, and that it had already received a number of patients. Middle Eastern neighbors including Qatar, Kuwait, the UAE and Iraq will also send field hospitals, medical supplies and oil to Lebanon, state-run NNA said.

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