Taking the stage at the Prudential Center in Newark, N.J., Elliott performed her hits including, "Pass That Dutch" and ''Lose Control." She even sported the inflated trash bag she first rocked with confidence and charisma in the 1997 video for "The Rain (Supa Dupa Fly)."
The 48-year-old also brought out Alyson Stoner — who was 10-years-old when she was first featured in Elliott's 2003 video "Work It" — for the performance.
"I've worked diligently for over two decades and I never thought I would be standing up here receiving this award," Elliott said while accepting the Michael Jackson Video Vanguard Award.
Video Vanguard recipient Missy Elliott performs a medley at the MTV Video Music Awards at the Prudential Center on Monday, Aug. 26, 2019, in Newark, N.J. (Photo by Matt Sayles/Invision/AP)
The rapper-singer-songwriter-producer-dancer said she wanted to dedicate the award to the dance community: "Y'all are not just props, y'all are the icing on the cake."
Elliott also honored the late R&B icon Aaliyah, whom she was close to and collaborated with, during her acceptance speech. The 18th anniversary of Aaliyah's death was Sunday.
"Aaliyah, I love you. We miss you," Elliott said.
Halsey, Bebe Rexha and Taylor Swift were among the audience members who danced wildly as Elliott blazed the stage.
The Associated Press contributed to this report